Auditory and Vestibular Technologies Core for translational hearing research
Official title: AVT Core: Component for Institution # P2500069
Funded at Creighton University · NIH-11336215 · Data updated 2026-11-12
A core facility at Creighton University helps researchers study hearing and balance by providing advanced instruments and expert support for experiments in mouse and zebrafish models.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Creighton University NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project start | March 5, 2021 |
| Project end | February 28, 2031 |
| Funding year | 2026 |
| Award (this year) | $304,393 |
| NIH project number | 2P20GM139762-06 |
| Project ID | NIH-11336215 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not a patient enrollment grant; applicable to researchers studying hearing and balance using animal models.
✕Less likely to help
Direct patient participation is not part of this grant.
What this research studies
This grant funds a dedicated core that offers cutting-edge tools and technical help for auditory and vestibular studies across scales—from molecules to whole organisms. It supports electrophysiology, molecular biology, imaging, and mass spectrometry to enable translational research in hearing and balance. Researchers can access mentoring and training to use these technologies effectively and secure future funding. The core plans to stay up-to-date with new technologies and expand services to a broader research community.
Why it matters
Potential benefit: If successful, patients could benefit from faster development of better hearing and balance therapies informed by integrated, multi-scale research.
How similar studies have gone: Other core facilities with multidisciplinary instrumentation have accelerated preclinical discoveries in auditory research.
Where this research is happening
-
Creighton University
Omaha, United States Active
Researchers
- Principal investigator: Nichols, Michael G — Creighton University
- Study coordinator: Nichols, Michael G
Related research
Other NIH-funded projects on the same topics.
-
Epigenetic control of brain development and behavior linked to KMT5B
A study to understand how changes in a gene called KMT5B affect brain development and behaviors related to autism, by looking at how this gene influences IGF signals in the brain and body.
-
Noise-related hearing loss and brain-to-ear feedback in hearing protection
A small, patient-friendly study will look at how loud noise changes the brain’s control over hearing and whether this affects conditions like tinnitus or sensitivity to sound.
-
Identifying which drugs used for infections and inflammation may harm hearing
Researchers are using computer models and animal studies to flag medicines that could cause hearing loss, with the goal of safer treatments for adults.
-
Redox regulation of Borrelia burgdorferi infectivity
Scientists are studying how the Lyme disease bacteria use redox signals to become infectious, with the aim of understanding how to prevent infection.
-
How prion strains might jump species and change over time
This research will explore how different prion strains and substrains could influence the spread of prion diseases to new animal hosts and possibly humans.
-
New approach to calm the airways in therapy-resistant asthma
A new small-molecule treatment targeting p63RhoGEF could reduce airway tightness and inflammation in people with asthma that doesn’t respond well to standard therapies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.