Assessing tools to prevent psychosis in at-risk individuals

ProCAN: Psychosis Risk Outcomes Compound Assessment Network

['FUNDING_U01'] · YALE UNIVERSITY · NIH-11117166

This study is looking for ways to help people who are at high risk of developing psychosis by finding new tools and treatments that can prevent these disorders from starting, so they can feel better and function well in their daily lives.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorYALE UNIVERSITY (nih funded)
Locations1 site (NEW HAVEN, UNITED STATES)
Trial IDNIH-11117166 on ClinicalTrials.gov

What this research studies

This research focuses on individuals at clinical high risk for psychosis, aiming to develop and validate tools that can help prevent the onset of psychotic disorders. By collaborating with various partners, the project seeks to identify biological, cognitive, and clinical measures that can be used in drug development. Patients will be monitored and assessed using these measures to determine their effectiveness in improving symptoms and overall functioning. The goal is to create a robust infrastructure that supports the development of new treatments for those at risk.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents and young adults identified as being at clinical high risk for developing psychotic disorders.

Not a fit: Patients who are not at risk for psychosis or who have already developed psychotic disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing psychosis in individuals at high risk, improving their quality of life.

How similar studies have performed: Previous initiatives like the Accelerating Medicines Partnership® Schizophrenia Observational Study have shown promise in developing tools for understanding and treating psychosis risk.

Where this research is happening

NEW HAVEN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: attenuated psychosis syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.