Assessing nerve damage during surgery using fluorescence

Rapid Intraoperative Fluorescence Assessment of Nerve Damage

['FUNDING_R21'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-10466056

This study is testing a new way for surgeons to see how badly nerves are hurt during surgeries for injuries like fractures or dislocations, using a special dye that lights up nerve tissue, which could help them make better decisions about treatment and improve recovery for patients.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorOREGON HEALTH & SCIENCE UNIVERSITY (nih funded)
Locations1 site (PORTLAND, UNITED STATES)
Trial IDNIH-10466056 on ClinicalTrials.gov

What this research studies

This research investigates a new method for evaluating nerve injuries that occur during traumatic events, such as fractures or dislocations. By using a specialized fluorescent dye that targets nerve tissue, surgeons can obtain real-time, objective assessments of nerve damage during surgery. This approach aims to improve decision-making regarding whether a nerve can recover or if more drastic measures, like amputation, are necessary. The goal is to enhance surgical outcomes and functional recovery for patients with nerve injuries.

Who could benefit from this research

Good fit: Ideal candidates for this research are trauma patients who have sustained acute peripheral nerve injuries due to fractures or dislocations.

Not a fit: Patients with chronic nerve injuries or those who do not have acute nerve damage may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better surgical decisions and improved recovery outcomes for patients with nerve injuries.

How similar studies have performed: Previous research has shown promise in using fluorescence-guided techniques for surgical applications, suggesting potential success for this novel approach.

Where this research is happening

PORTLAND, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.