Assessing liver health in patients with non-alcoholic fatty liver disease using a new scoring tool.

Stratification of Non-alcoholic Fatty Liver Disease using the SAFE Score

['FUNDING_R01'] · STANFORD UNIVERSITY · NIH-10695181

This study is looking at a new tool called the SAFE score to help doctors find out which adults with non-alcoholic fatty liver disease are at risk for serious liver issues, so they can get the right care while others can skip extra tests.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorSTANFORD UNIVERSITY (nih funded)
Locations1 site (STANFORD, UNITED STATES)
Trial IDNIH-10695181 on ClinicalTrials.gov

What this research studies

This research focuses on non-alcoholic fatty liver disease (NAFLD), a condition affecting many adults that can lead to serious liver problems. The study aims to develop and validate a new tool called the SAFE score, which helps identify patients at risk of severe liver complications. By stratifying patients based on their risk, those who need specialized care can be directed appropriately, while others may avoid unnecessary tests. The research will involve testing this score in different patient groups to ensure its effectiveness.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults diagnosed with non-alcoholic fatty liver disease, particularly those with varying degrees of liver fibrosis.

Not a fit: Patients without non-alcoholic fatty liver disease or those with advanced liver disease requiring immediate intervention may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better management of NAFLD, allowing for timely interventions for those at risk of severe liver disease.

How similar studies have performed: Previous research has shown promise in using scoring systems for liver disease assessment, indicating that this approach may be effective.

Where this research is happening

STANFORD, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Diabetes Mellitus, diabetes, Non-Insulin-Dependent Diabetes Mellitus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.