Assessing kidney disease progression in children with ARPKD
Imaging Assessments of ARPKD Kidney Disease Progression
This study is looking at a kidney condition called Autosomal Recessive Polycystic Kidney Disease (ARPKD) in kids and aims to create better imaging tools to track how the disease changes over time, helping doctors understand its effects and find better treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11062499 on NIH RePORTER |
What this research studies
This research focuses on Autosomal Recessive Polycystic Kidney Disease (ARPKD), a serious inherited condition affecting children's kidneys. The study aims to develop sensitive imaging techniques to monitor kidney disease progression, which is crucial for understanding how the disease evolves and for evaluating potential treatments. By utilizing advanced imaging assessments, the research seeks to provide better insights into the disease's impact on kidney function over time. This approach is particularly important as current methods are inadequate for detecting subtle changes in kidney health in ARPKD patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are children diagnosed with Autosomal Recessive Polycystic Kidney Disease, particularly those under the age of 18.
Not a fit: Patients with other forms of kidney disease or those who are not diagnosed with ARPKD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment strategies for children with ARPKD, potentially delaying or preventing the progression to end-stage kidney disease.
How similar studies have performed: Previous research has shown success in using advanced imaging techniques for monitoring kidney disease in other conditions, suggesting potential applicability in ARPKD.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Dell, Katherine Macrae — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Dell, Katherine Macrae
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.