Assessing immune status using small amounts of blood plasma
High-throughput proteomics using submicroliter amounts of plasma for comprehensive assessment of the immune status
['FUNDING_OTHER'] · BOSTON CHILDREN'S HOSPITAL · NIH-10843777
This study is working on a new way to check how well your immune system is working using just a tiny bit of blood, which is especially helpful for older adults and premature babies who might not be able to give much blood.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON CHILDREN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10843777 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a new method to evaluate the immune system by using very small amounts of blood plasma. It aims to combine multiple tests that typically require larger samples into a single analysis, which is particularly beneficial for vulnerable populations like the elderly or premature newborns. By using a common processing platform, the study seeks to reduce the volume of blood needed for testing while still providing comprehensive immune assessments. This innovative approach could lead to more efficient and less invasive testing methods for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include elderly individuals and premature newborns who may have limited blood volume for testing.
Not a fit: Patients who do not fall into vulnerable categories, such as healthy adults with sufficient blood volume for testing, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enable more accurate and less invasive immune assessments for patients with limited blood samples.
How similar studies have performed: Other research has shown promise in developing sample-sparing assays, indicating that this approach could be effective.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON CHILDREN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: STEEN, HANNO — BOSTON CHILDREN'S HOSPITAL
- Study coordinator: STEEN, HANNO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: bacteria infection