Assessing how fluid flows in the eye to improve glaucoma treatment
Quantitative assessment of glaucomatous conventional outflow dynamics
This study is looking at how fluid flows in the eye to help people with glaucoma, using special imaging technology to see changes in eye tissues over time, with the hope of finding better ways to manage eye pressure and protect vision.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10978370 on NIH RePORTER |
What this research studies
This research investigates the dynamics of fluid outflow in the eye, specifically focusing on the conventional outflow pathway that regulates intraocular pressure (IOP) in glaucoma patients. By utilizing advanced imaging techniques like near-infrared optical coherence tomography (OCT) and artificial intelligence, the study aims to visualize and analyze the structural and functional changes in eye tissues over time. This approach seeks to provide a more comprehensive understanding of how glaucoma affects fluid dynamics, which could lead to improved treatment strategies for managing IOP and preventing vision loss.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with primary open-angle glaucoma, particularly those experiencing elevated intraocular pressure.
Not a fit: Patients with other forms of glaucoma or those who do not have elevated intraocular pressure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for glaucoma, potentially reducing the risk of blindness for patients.
How similar studies have performed: Previous research using similar imaging techniques has shown promise in understanding eye dynamics, suggesting that this approach could yield valuable insights.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Farsiu, Sina — Duke University
- Study coordinator: Farsiu, Sina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.