Assessing heart health in children and adults with lupus
Official title: Cardiovascular health assessment & outcomes of systemic lupus erythematosus: bridging pediatric and adult- onset disease
Funded at Boston Children's Hospital · NIH-10844640 · Data updated 2026-11-12
This study is looking at how lupus that starts in childhood can impact heart health, especially by checking nighttime blood pressure, to find ways to help improve heart health for those living with lupus.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 1, 2020 |
| Project end | December 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $168,016 |
| NIH project number | 5K23HL148539-05 |
| Project ID | NIH-10844640 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include children and young adults diagnosed with systemic lupus erythematosus.
✕Less likely to help
Patients without a diagnosis of systemic lupus erythematosus or those with other unrelated cardiovascular conditions may not benefit from this research.
What this research studies
This research investigates how systemic lupus erythematosus (SLE), particularly when it begins in childhood, affects cardiovascular health. It focuses on measuring nocturnal blood pressure decline using ambulatory blood pressure monitoring, which may indicate early cardiovascular risk. The study aims to identify the mechanisms behind increased cardiovascular risk in these patients and explore potential treatments that could improve vascular health. By understanding these factors, the research hopes to develop effective interventions to enhance heart health in individuals with lupus.
Why it matters
Potential benefit: If successful, this research could lead to improved cardiovascular health and reduced disease complications for patients with lupus.
How similar studies have gone: Previous research has shown that monitoring nocturnal blood pressure can be a valuable tool in assessing cardiovascular risk, indicating that this approach has potential for success.
Where this research is happening
-
Boston Children's Hospital
Boston, United States Active
Researchers
- Principal investigator: Chang, Joyce Chun-Ling — Boston Children's Hospital
- Study coordinator: Chang, Joyce Chun-Ling
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.