Assessing heart function during exercise in patients with atrial fibrillation after treatment.
Official title: EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation TO Reduce Atrial Fibrillation Burden and Correlation with Exercise CapacitY: EXCLAMATORY Longitudinal Study
Funded at Virginia Commonwealth University · NIH-10906112 · Data updated 2026-11-12
This study is looking at how exercise impacts heart function in people with atrial fibrillation after they have had a procedure called catheter ablation, to help understand how their hearts perform during physical activity and improve their daily lives.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $181,605 |
| NIH project number | 5K23HL166956-02 |
| Project ID | NIH-10906112 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with atrial fibrillation who have undergone catheter ablation treatment.
✕Less likely to help
Patients who do not have atrial fibrillation or those who have not undergone catheter ablation may not benefit from this research.
What this research studies
This research investigates how exercise affects heart function in patients with atrial fibrillation, particularly after they have undergone a treatment called catheter ablation. By using advanced imaging techniques, the study aims to measure the heart's performance during physical activity, which is often overlooked in traditional assessments. The goal is to understand how these changes in heart function relate to patients' ability to engage in daily activities and to identify potential new treatment targets. Patients will be monitored over time to see how their heart function evolves with exercise.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for patients with atrial fibrillation, enhancing their quality of life and exercise capacity.
How similar studies have gone: Previous research has shown promise in using exercise-based assessments to evaluate heart function, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Virginia Commonwealth University
Richmond, United States Active
Researchers
- Principal investigator: Trankle, Cory — Virginia Commonwealth University
- Study coordinator: Trankle, Cory
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.