Assessing glioblastoma response using advanced MRI techniques
Official title: Response assessment of glioblastoma using magnetic resonance elastography
Funded at Massachusetts General Hospital · NIH-11072030 · Data updated 2026-11-12
This study is looking at how a special imaging technique called magnetic resonance elastography (MRE) can help doctors better understand glioblastoma, a tough brain tumor, by creating detailed maps of the tumor's characteristics to tell the difference between real growth and treatment-related changes, ultimately aiming to improve treatment decisions and outcomes for patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $195,181 |
| NIH project number | 5R21CA282393-02 |
| Project ID | NIH-11072030 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with glioblastoma who are undergoing treatment and require imaging assessments.
✕Less likely to help
Patients with other types of brain tumors or those who are not undergoing treatment for glioblastoma may not benefit from this research.
What this research studies
This research investigates how magnetic resonance elastography (MRE) can improve the assessment of glioblastoma, a highly aggressive brain tumor. By using MRE, the study aims to create detailed 3D maps of the tumor's mechanical properties, which may help differentiate between true tumor progression and pseudoprogression, a common complication in treatment. This approach seeks to provide earlier and more accurate information to guide treatment decisions, potentially leading to better patient outcomes. The research will involve analyzing patient data and imaging results to validate the effectiveness of MRE in clinical settings.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of glioblastoma progression, allowing for timely and effective treatment adjustments.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques like MRE for tumor assessment, indicating potential for success in this novel application.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Deng, Bin — Massachusetts General Hospital
- Study coordinator: Deng, Bin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.