Assessing genetic risk factors for breast cancer in women of African descent
Official title: Core C : Population Genomic Risk Assessment
Funded at University of California, San Francisco · NIH-10935794 · Data updated 2026-11-12
This study is looking at how your genes might affect your risk of breast cancer, especially for women of African ancestry, to help create better screening and prevention plans just for you.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 11, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $145,954 |
| NIH project number | 1P01CA281826-01A1 |
| Project ID | NIH-10935794 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women of African ancestry who are interested in understanding their genetic risk for breast cancer.
✕Less likely to help
Patients who do not identify as having African ancestry may not benefit from this specific research.
What this research studies
This research focuses on using polygenic risk scores (PRS) to evaluate the genetic risk of breast cancer among women of African ancestry. By analyzing genetic variants associated with breast cancer, the study aims to improve risk stratification and screening practices. Participants will contribute to the collection of high-quality genotype data, which will be integrated into personalized risk assessments for breast cancer subtypes. The goal is to enhance early detection and tailored screening recommendations based on individual genetic profiles.
Why it matters
Potential benefit: If successful, this research could lead to more accurate breast cancer screening and prevention strategies for women of African descent.
How similar studies have gone: Previous research has shown promise in using polygenic risk scores for breast cancer risk assessment, indicating that this approach could be effective.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Ziv, Elad — University of California, San Francisco
- Study coordinator: Ziv, Elad
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.