Assessing brain health with portable MRI technology
Official title: Measuring Brain Health Using Low-Field Portable MRI
Funded at Yale University · NIH-10950708 · Data updated 2026-11-12
This study is looking to make it easier and more affordable to check for brain health issues like stroke and Alzheimer's by using a new type of portable MRI to measure white matter hyperintensities, and it’s for anyone interested in understanding their brain health better.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $476,993 |
| NIH project number | 1R21NS138995-01 |
| Project ID | NIH-10950708 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who may be at risk for Alzheimer's disease or related dementias.
✕Less likely to help
Patients who are not at risk for Alzheimer's disease or related dementias may not receive any benefit from this research.
What this research studies
This research focuses on improving the measurement of white matter hyperintensity (WMH), a key indicator of stroke and Alzheimer's disease risk, using low-field portable MRI (pMRI). The study aims to develop a new qualitative scale and a machine learning-based quantitative method for assessing WMH specifically tailored for pMRI. Participants will undergo both pMRI and conventional high-field MRI to validate the new measurement techniques. This innovative approach could make brain health assessments more accessible and cost-effective.
Why it matters
Potential benefit: If successful, this research could lead to more accessible and accurate assessments of brain health, particularly for those at risk of Alzheimer's disease and related dementias.
How similar studies have gone: Previous research has shown promise in using machine learning and advanced imaging techniques for brain health assessments, indicating potential success for this novel approach.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: De Havenon, Adam H. — Yale University
- Study coordinator: De Havenon, Adam H.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.