Assessing brain function in children with HIV in low-income countries

Building Resources to Assess Impaired Neurocognition in Children with HIV in Low- and Middle-Income Countries (BRAIN Child in LMICs)

NIH-funded research New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · NIH-10471974

This study is looking at how HIV affects the brain development of children in Uganda, aiming to create easy-to-use tests that help identify any learning or social challenges these kids might face, so we can better support them in their education and daily lives.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionNew York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10471974 on NIH RePORTER

What this research studies

This research focuses on understanding how HIV affects the brain development of children living in low- and middle-income countries, particularly in Uganda. It aims to identify neurocognitive impairments that these children may experience, which can impact their education, social interactions, and overall quality of life. The study will develop and validate neurocognitive tests that are culturally appropriate and feasible for use in Uganda, allowing for better detection and understanding of these impairments. By addressing these challenges, the research seeks to improve the support and resources available for children with HIV.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 5-12 years living with perinatally-acquired HIV in Uganda.

Not a fit: Patients who are not living with HIV or are outside the age range of 5-12 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved detection and management of neurocognitive impairments in children with HIV, enhancing their educational and social outcomes.

How similar studies have performed: Similar research has shown success in identifying neurocognitive impairments in children with chronic illnesses, suggesting that this approach could be effective in the context of HIV.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.