Assessing bone quality using advanced CT imaging techniques
Official title: Comprehensive assessment of bone quality using clinical photon-counting detector CT
Funded at Mayo Clinic Rochester · NIH-11057087 · Data updated 2026-11-12
This study is looking at a new way to take detailed pictures of bones to help people at risk for osteoporosis understand their bone strength better, which could lead to improved care and treatment.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | September 20, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $391,588 |
| NIH project number | 1R21AR084126-01A1 |
| Project ID | NIH-11057087 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults over 21 years old who are at risk for osteoporosis, including those with conditions like plasma cell disorders or lupus.
✕Less likely to help
Patients who are not at risk for osteoporosis or do not have conditions affecting bone density may not benefit from this research.
What this research studies
This research focuses on improving the evaluation of bone quality in individuals at risk for osteoporosis, a condition affecting millions of Americans. By utilizing a new imaging technology called photon-counting detector CT, the study aims to provide detailed insights into the microarchitecture of bones, which is crucial for understanding bone strength and fracture risk. The approach involves capturing high-resolution images that can reveal important structural details that traditional methods may miss. This could lead to better diagnosis and management of osteoporosis and related conditions.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of bone health, potentially reducing the risk of fractures and improving patient outcomes.
How similar studies have gone: Previous research has shown promising results using advanced imaging techniques for bone assessment, indicating that this approach could be a significant advancement in the field.
Where this research is happening
-
Mayo Clinic Rochester
Rochester, United States Active
Researchers
- Principal investigator: Rajendran, Kishore — Mayo Clinic Rochester
- Study coordinator: Rajendran, Kishore
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.