Assessing bladder cancer treatment response using urine tests
Personalized assessment of bladder cancer treatment response using urinary molecular biomarkers
This study is working on a new, easy urine test to help diagnose and treat bladder cancer better, especially for veterans who are more likely to get it, by looking for specific markers in the urine that can guide personalized treatment plans.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Admin Palo Alto Health Care Sys NIH-funded |
| Lab location | 1 site (Palo Alto, United States) |
| Project ID | NIH-11184153 on NIH RePORTER |
What this research studies
This research focuses on improving the diagnosis and treatment of bladder cancer by developing non-invasive urine tests that measure molecular biomarkers. The goal is to create personalized treatment strategies for patients with localized bladder cancer, particularly benefiting veterans who are at higher risk. By analyzing tumor-derived nucleic acids found in urine, the research aims to provide more accurate assessments of disease burden and treatment response. The methodology includes high throughput RNA sequencing and the use of advanced microfluidics technology for rapid results.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with localized bladder cancer, especially veterans with a history of tobacco use or environmental exposure.
Not a fit: Patients with advanced bladder cancer or those not diagnosed with bladder cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for bladder cancer patients, reducing the need for invasive procedures.
How similar studies have performed: Previous research has shown promise in using molecular biomarkers for cancer diagnosis, indicating that this approach could be effective.
Where this research is happening
Palo Alto, United States
- Veterans Admin Palo Alto Health Care Sys — Palo Alto, United States (Active)
Researchers
- Principal investigator: Liao, Joseph C — Veterans Admin Palo Alto Health Care Sys
- Study coordinator: Liao, Joseph C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.