Arizona Alzheimer's Clinical Core: tracking memory, genetics, and blood tests
Core B: Clinical Core
This program follows people with and without memory problems to help create simple blood tests and speed up prevention efforts for Alzheimer's, with attention to APOE genetic types.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arizona State University-Tempe Campus NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project ID | NIH-11137600 on NIH RePORTER |
What this research studies
If you join, you will have regular visits for memory exams, blood draws, and sometimes spinal fluid collection or brain-donation enrollment, with your results entered into a shared database. The program combines about 1,650 people followed over time from five sites around Phoenix and Tucson, including many from Hispanic/Latino and Native American communities. The team focuses on blood-based biomarkers and APOE genetic groups to identify early signs of Alzheimer's and to make prevention trials faster. Data and samples are shared across the consortium to support many linked prevention and biomarker projects.
Who could benefit from this research
Good fit: Adults who are cognitively unimpaired, have mild cognitive impairment, or have dementia—especially people with APOE-e4 alleles or those from Hispanic/Latino and Native American communities in the Phoenix/Tucson area—are ideal candidates.
Not a fit: People who live far from Arizona, cannot travel to Phoenix/Tucson, or decline blood/CSF sampling or brain donation may not be able to participate or receive direct benefit.
Why it matters
Potential benefit: If successful, this work could lead to blood tests that detect Alzheimer's changes earlier and make preventive treatments available sooner.
How similar studies have performed: Related efforts using blood biomarkers and APOE-focused cohorts have shown promising early results, but these approaches are still being validated for routine clinical use.
Where this research is happening
Scottsdale, United States
- Arizona State University-Tempe Campus — Scottsdale, United States (Active)
Researchers
- Principal investigator: Atri, Alireza — Arizona State University-Tempe Campus
- Study coordinator: Atri, Alireza
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.