Appalachian and Mid‑Atlantic Addiction Treatment Network

Appalachian Node

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-11261207

This network runs clinical trials and care projects to find better treatments and supports for people with substance use disorders in Appalachia and nearby cities.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-11261207 on NIH RePORTER

What this research studies

If you live in central Appalachia or a nearby city, this program tests new treatments and support programs for people who use drugs. Teams from the University of Pittsburgh, West Virginia University, Penn State, and the University of Maryland partner with a shared electronic health record network to reach both rural and urban communities like Baltimore, Philadelphia, Detroit, and Chicago. The Node conducts community‑informed clinical trials, collects health record and outcome data, and compares which interventions work best in different places. The group has led many prior trials and offers opportunities to join treatment studies at participating medical centers.

Who could benefit from this research

Good fit: Ideal candidates are adults with opioid or other substance use disorders who can attend visits at participating hospitals or clinics in Appalachia or the mid‑Atlantic/urban partner cities.

Not a fit: People without substance use disorders, those unable to travel to participating sites, or those who do not meet trial eligibility criteria are unlikely to receive direct benefit from participation.

Why it matters

Potential benefit: If successful, this work could lead to more effective treatments and support services that reduce overdoses and help people stay in recovery.

How similar studies have performed: The Node has led and joined multiple NIDA CTN trials with strong recruitment and a substantial publication record, so similar approaches have produced useful results previously.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.