App-based support for managing Alzheimer's behaviors

I-CARE 2 RCT: Mobile Telehealth to Reduce Alzheimer's-related Symptoms for Caregivers and Patients

NIH-funded research Trustees of Indiana University · NIH-11178672

A mobile app to help caregivers manage Alzheimer-related behaviors and reduce stress for caregivers and patients.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionTrustees of Indiana University NIH-funded
Lab location1 site (Bloomington, United States)
Project IDNIH-11178672 on NIH RePORTER

What this research studies

This trial tests a smartphone telehealth app called Brain CareNotes that gives caregivers guidance and tools for handling behavioral and psychological symptoms of dementia such as agitation, aggression, and mood changes. You and your caregiver would be randomly assigned to use the app or to usual care, and the study team will follow symptoms and caregiver burden over time. The team previously ran a small pilot that showed reduced caregiver stress and fewer behavioral problems at six months. This larger randomized trial aims to confirm those benefits in more people and settings.

Who could benefit from this research

Good fit: People living with Alzheimer disease or related dementias who have an informal caregiver willing to use a smartphone app and who experience behavioral or psychological symptoms would be ideal candidates.

Not a fit: People without an available informal caregiver, without reliable access to a smartphone or internet, or whose symptoms are primarily driven by acute medical issues may not receive benefit from this intervention.

Why it matters

Potential benefit: If successful, the app could reduce upsetting behaviors in people with dementia and lower caregiver stress and burden.

How similar studies have performed: A prior pilot of Brain CareNotes showed reduced caregiver burden and behavioral symptoms at six months, but larger randomized trials are still limited.

Where this research is happening

Bloomington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.