NIH-funded research NIH-funded research

Antibiotics for Breastfeeding Mothers: Understanding Impact on Milk, Babies, and Gut Health

Official title: Antibiotic Treatment in Breastfeeding Mothers: Effects on Milk, Microbiome, and Infant Outcomes

Funded at University of California, San Diego · NIH-11143899 · Data updated 2026-11-12

This research aims to understand how common antibiotics taken by breastfeeding mothers might affect their breast milk, their baby's gut health, and the baby's overall development.

More Breastfeeding research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startSeptember 10, 2021
Project endJuly 31, 2026
Funding year2025
Award (this year)$180,225
NIH project number5P50HD106463-05
Project IDNIH-11143899 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are breastfeeding mothers and their infants who may be taking or considering taking commonly prescribed antibiotics.

Less likely to help

Patients who are not breastfeeding or whose infants are older than one year may not directly benefit from this particular research.

What this research studies

We want to learn more about how antibiotics pass into breast milk and what changes they might cause in the milk's nutrients and beneficial bacteria. We also hope to discover how a mother's antibiotic use could influence her baby's growth, development, and immune system. To do this, we will follow mothers and their babies, collecting samples and observing their health over time. This will help us understand the full picture of antibiotic use during breastfeeding.

Why it matters

Potential benefit: If successful, this work could provide clearer guidance for breastfeeding mothers and their doctors regarding antibiotic use, potentially improving infant health outcomes.

How similar studies have gone: While antibiotic use in breastfeeding is common, there is limited comprehensive research specifically on the transmission, milk composition changes, and long-term infant outcomes, making this a novel and important area of inquiry.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Chambers, Christina — University of California, San Diego
  • Study coordinator: Chambers, Christina

Related research

Other NIH-funded projects on the same topics.

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  • Breastfeeding Education Support Tool for Baby

    A community-based program in India trains mothers with peer counselors and a mobile app to support exclusive breastfeeding for 6 months and promote healthy growth and development.

    NIH research Thomas Jefferson University · Philadelphia, United States · NIH-11474437

  • Promoting Breastfeeding to Prevent Postpartum Smoking Relapse

    A trial tests whether encouraging new mothers to breastfeed helps prevent them from starting to smoke again after giving birth.

    NIH research State University of New York at Buffalo · Amherst, United States · NIH-11400074

  • Breastfeeding support to reduce obesity risk in children

    A family-based program helps new Hispanic mothers in the WIC program breastfeed more and give babies a healthier start to prevent obesity and diabetes later.

    NIH research University of North Carolina Greensboro · Greensboro, United States · NIH-11397000

  • Transdermal HIV prevention for breastfeeding infants using bnAbs on a patch

    A child-focused HIV prevention approach uses a patch to deliver protective antibodies through the skin to babies who are breastfed.

    NIH research Old Dominion University · Norfolk, United States · NIH-11395232

  • Breastfeeding, Microbiome, and Early-Life Respiratory Health

    A study to see how a baby’s gut and nose bacteria, influenced by breastfeeding, relate to the risk of chest infections and asthma as they grow.

    NIH research New York University School of Medicine · New York, United States · NIH-11392247

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.