Analyzing treatment effectiveness and safety for COPD patients using real-world data
Official title: Improving COPD Outcomes: Using Real-World Data to Analyze Treatment Effectiveness, Safety, and Adherence
Funded at Brigham and Women's Hospital · NIH-11001495 · Data updated 2026-11-12
This study looks at how well different COPD treatments work in real life, focusing on why patients stick to their inhaler routines and which options are the safest and most effective for everyday use, all to help improve care for people with COPD.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | December 19, 2022 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $165,741 |
| NIH project number | 5K08HL163246-03 |
| Project ID | NIH-11001495 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with chronic obstructive pulmonary disease (COPD) who are receiving treatment.
✕Less likely to help
Patients with COPD who are not currently receiving treatment or those with very early-stage disease may not benefit from this research.
What this research studies
This research investigates how well different treatments for chronic obstructive pulmonary disease (COPD) work in everyday clinical settings, rather than just in controlled clinical trials. It aims to understand the reasons behind patients' adherence to inhaler therapies and to identify which treatments are most effective and safe for patients in real life. By analyzing real-world data, the study seeks to provide insights that can help improve the management of COPD and enhance patient care.
Why it matters
Potential benefit: If successful, this research could lead to better treatment strategies for COPD, improving patients' quality of life and health outcomes.
How similar studies have gone: Previous research has shown that real-world data can provide valuable insights into treatment effectiveness, suggesting that this approach has the potential for success.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Feldman, William Brand — Brigham and Women's Hospital
- Study coordinator: Feldman, William Brand
Related research
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-
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A broad AI model uses diverse health data to help predict and manage COPD in people, with an emphasis on ethics and fairness.
-
Easier, local pulmonary rehab and social support for people with COPD in low-resource clinics
This project compares a 10-week community pulmonary rehabilitation program alone, the same program plus help with social needs, and usual care for people with moderate-to-severe COPD to see which helps people stick with rehab and feel better.
-
Improving COPD outcomes with real-world data
A doctor-scientist at a major university is using real-world information from COPD patients to understand which treatments work best, how safe they are, and whether people stick to their inhaler plans.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.