Analyzing tiny particles to find markers of aging and resilience
Extracellular Vesicle Analyses to Develop Aging and Resilience Biomarkers
This study is looking at tiny particles released by our cells to find signs of aging and how well our bodies cope with stress, specifically in people aged 65 and older.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11003718 on NIH RePORTER |
What this research studies
This research investigates extracellular vesicles (EVs), which are small particles released by cells into bodily fluids. By analyzing these vesicles, the study aims to identify biomarkers that indicate aging and resilience in individuals, particularly those aged 65 and older. The research employs advanced techniques such as high-resolution flow cytometry and nanoparticle tracking to evaluate existing human samples. The ultimate goal is to understand how these biomarkers can reflect the aging process and the body's response to stressors.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who are interested in understanding their aging process and resilience.
Not a fit: Patients younger than 65 years old may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new ways to assess and improve health outcomes for older adults.
How similar studies have performed: Previous research has shown promise in using extracellular vesicles as biomarkers, indicating that this approach may lead to significant findings.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Kraus, Virginia — Duke University
- Study coordinator: Kraus, Virginia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.