Analyzing tiny particles from pancreatic cells related to Type 1 Diabetes
Micro-nanotechnologies for the analysis of islet-derived extracellular vesicles implicated in Type 1 Diabetes
This study is looking at tiny particles from pancreatic cells to see if they can help us learn more about Type 1 Diabetes, and we’d love to have patients share samples to help us find new ways to diagnose the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-10897218 on NIH RePORTER |
What this research studies
This research focuses on understanding how small particles called extracellular vesicles (EVs) released by pancreatic cells can provide insights into Type 1 Diabetes (T1D). By using advanced technologies, the researchers will analyze the molecular content of these EVs from both healthy individuals and those with T1D. The goal is to identify specific proteins and genetic materials that could serve as biomarkers for T1D, helping to understand the disease better and potentially leading to new diagnostic methods. Patients may be involved in providing samples to help with this analysis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Type 1 Diabetes as well as healthy individuals for comparison.
Not a fit: Patients with other forms of diabetes or those without any pancreatic issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new diagnostic tools for early detection and monitoring of Type 1 Diabetes.
How similar studies have performed: Previous research has shown promise in using extracellular vesicles for biomarker discovery in various diseases, suggesting a potential for success in this novel approach.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Ng, Alphonsus — University of Utah
- Study coordinator: Ng, Alphonsus
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.