Analyzing tiny particles from cells for better diagnostics and therapies
Official title: High-Throughput High-Content Nanoscale Extracellular Vesicle Analysis
Funded at Numentus Technologies INC. · NIH-11008373 · Data updated 2026-11-12
This study is exploring a new way to look at tiny particles released by cells that can provide important clues about cancer and infections, with the goal of helping doctors find better ways to diagnose and treat patients.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Numentus Technologies INC. NIH-funded |
| Lab location | 1 site (Menlo Park, United States) |
| Project start | July 5, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $298,999 |
| NIH project number | 1R43GM156162-01 |
| Project ID | NIH-11008373 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients with cancer or bacterial infections who may benefit from advanced diagnostic techniques.
✕Less likely to help
Patients with conditions unrelated to cancer or bacterial infections may not receive direct benefits from this research.
What this research studies
This research focuses on extracellular vesicles (EVs), which are small particles released by cells that carry important biological information. The project aims to develop a new technology that can identify and analyze different types of EVs, particularly those related to cancer and bacterial infections, at a very detailed level. By using advanced imaging techniques, the researchers hope to distinguish between various subpopulations of EVs, which could lead to improved diagnostic tools and treatment options for patients. The approach involves examining the surface proteins of these particles to gather critical data from clinical samples.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnostics and targeted therapies for cancer and other diseases.
How similar studies have gone: Other research has shown promise in using similar high-throughput analysis techniques for studying extracellular vesicles, indicating potential for success in this approach.
Where this research is happening
-
Numentus Technologies INC.
Menlo Park, United States Active
Researchers
- Principal investigator: Faris, Gregory W — Numentus Technologies INC.
- Study coordinator: Faris, Gregory W
Related research
Other NIH-funded projects on the same topics.
-
Multiplexed blood biomarkers for Alzheimer’s disease subtypes
A new test uses many extracellular vesicle signals from blood to help identify different Alzheimer’s subtypes and guide better diagnosis.
-
Developing a faster and more versatile PCR method for DNA and RNA testing
This study is working on a new, faster, and more portable machine to help doctors quickly test for infections like the flu by improving how we copy DNA and RNA, so patients can get their results in just minutes instead of hours.
-
Developing fast imaging techniques to analyze brain tissue for Alzheimer's disease
This study is looking at new ways to take pictures of brain tissue to help doctors better understand and diagnose Alzheimer's disease, so patients can get more accurate and effective treatments.
-
Exploring bacterial outer membrane vesicles for diagnostics and therapies
This study is exploring how tiny bubbles released by bacteria could help us find and treat infections better by looking closely at what’s inside them, making it easier to identify specific bacterial infections.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.