Analyzing the timing of disease onset in cohort studies
Semiparametric Regression Analysis of Interval-Censored Data in Current Cohort Studies
['FUNDING_R01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11051189
This study is looking at new ways to understand how diseases like diabetes and cancer develop over time when we can't pinpoint exactly when they start, so we can help improve health outcomes for people at risk.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-11051189 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced statistical models to analyze data from cohort studies where the onset of diseases like diabetes or cancer cannot be pinpointed exactly but is known to occur between two medical examinations. By creating semiparametric regression models, the research aims to better understand how these diseases progress over time and their impact on future health outcomes. The study will also explore methods to validate these models and improve the accuracy of data analysis in epidemiological research.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are part of cohort studies and are at risk for diseases such as diabetes, hypertension, or cancer.
Not a fit: Patients with well-defined disease onset or those not participating in cohort studies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate predictions of disease onset and progression, ultimately improving patient care and treatment strategies.
How similar studies have performed: Previous research has shown promise in using advanced statistical methods for analyzing interval-censored data, indicating that this approach could yield valuable insights.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZENG, DONGLIN — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: ZENG, DONGLIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, Cardiac Diseases, Cardiac Disorders