Analyzing the safety of drugs used in cancer treatment
Official title: Meta-analysis of Adverse Drug Effects in Clinical Trials
Funded at Pennsylvania State Univ Hershey Med Ctr · NIH-11110343 · Data updated 2026-11-12
This study is looking at the side effects of cancer immunotherapy drugs by gathering information from different clinical trials, so that patients can have a clearer understanding of the risks involved and make better choices about their treatment.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project start | June 7, 2024 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $203,398 |
| NIH project number | 5R21LM014534-02 |
| Project ID | NIH-11110343 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include cancer patients undergoing immunotherapy who are concerned about the potential side effects of their treatment.
✕Less likely to help
Patients who are not receiving cancer immunotherapy or those with conditions unrelated to the adverse effects of drug treatments may not benefit from this research.
What this research studies
This research focuses on understanding the adverse effects of drugs used in cancer immunotherapy by combining data from multiple clinical trials. By using advanced statistical methods, the project aims to identify and assess the risks associated with these adverse events in a larger and more diverse patient population. The goal is to improve the accuracy of safety information, which is crucial for making informed treatment decisions. Patients can benefit from a better understanding of the potential risks of their treatments.
Why it matters
Potential benefit: If successful, this research could lead to improved safety profiles for cancer treatments, helping patients make more informed choices about their care.
How similar studies have gone: Previous research using meta-analytic methods to assess drug safety has shown promise, indicating that this approach could yield valuable insights.
Where this research is happening
-
Pennsylvania State Univ Hershey Med Ctr
Hershey, United States Active
Researchers
- Principal investigator: Zhou, Shouhao — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Zhou, Shouhao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.