Analyzing the immune environment of lung cancer for better diagnosis and treatment
Quantitative and Spatially-Resolved Analysis of the Tumor Immune Contexture for Optimal Diagnosis and Treatment of Lung Cancer
This study is looking at how the immune system works with non-small cell lung cancer to find new ways to help patients get better treatments, especially for those who haven't had success with current options.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10894034 on NIH RePORTER |
What this research studies
This research investigates how the immune system interacts with lung cancer, particularly focusing on non-small cell lung cancer (NSCLC). The team aims to identify new biomarkers that can help select the right patients for immunotherapy and explore new treatment targets beyond current therapies. By studying the immune response and specific pathways involved in tumor progression, the research seeks to improve treatment options for patients who do not respond to existing therapies. Patients may benefit from insights that could lead to more effective personalized treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with non-small cell lung cancer, especially those who have not responded to standard PD-1 therapies.
Not a fit: Patients with lung cancer types other than non-small cell lung cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and outcomes for lung cancer patients, particularly those who currently have limited options.
How similar studies have performed: Previous research has shown promise in targeting immune pathways in cancer treatment, suggesting that this approach could yield significant advancements.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Schalper, Kurt a — Yale University
- Study coordinator: Schalper, Kurt a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.