Analyzing specific forms of the Akt protein in live cells
Official title: Live Cell Isoform-specific Akt Analyses
Funded at Texas Tech University · NIH-11037142 · Data updated 2026-11-12
This study is looking at different versions of a protein called Akt in living cells to learn how they work together, which could help develop better treatments for patients in the future.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas Tech University NIH-funded |
| Lab location | 1 site (Lubbock, United States) |
| Project start | September 10, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $99,738 |
| NIH project number | 3R15GM147858-01A1S1 |
| Project ID | NIH-11037142 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for potential benefit are individuals with conditions linked to Akt protein abnormalities, such as certain cancers or metabolic disorders.
✕Less likely to help
Patients with conditions unrelated to Akt protein functions may not receive any direct benefit from this research.
What this research studies
This research focuses on the analysis of different isoforms of the Akt protein within live cells. By acquiring advanced equipment, the study aims to enhance our understanding of how these protein variants function and interact in cellular processes. Patients may benefit indirectly through improved knowledge that could lead to better-targeted therapies in the future. The methodology involves live cell imaging and biochemical assays to observe the behavior of these protein isoforms in real-time.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for diseases related to Akt protein dysfunction.
How similar studies have gone: While this specific approach is focused on isoform-specific analysis, similar studies have shown promise in understanding protein functions and their implications in disease.
Where this research is happening
-
Texas Tech University
Lubbock, United States Active
Researchers
- Principal investigator: Wang, Degeng — Texas Tech University
- Study coordinator: Wang, Degeng
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.