Analyzing retinal imaging data from premature infants and healthy term infants

Secondary Data Analysis for Neonates with Retinal OCT Imaging

NIH-funded research Duke University · NIH-10707461

This study looks at data from 330 babies, some at risk for Retinopathy of Prematurity (ROP) and some healthy, to learn more about their eye health using special imaging technology, with the hope of improving care for infants with ROP.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-10707461 on NIH RePORTER

What this research studies

This research involves analyzing existing data from 330 infants, including those at risk for Retinopathy of Prematurity (ROP) and healthy term infants, who were previously enrolled in studies using advanced imaging technology called Optical Coherence Tomography (OCT). The goal is to better understand the retinal health of these infants by comparing the two groups and identifying potential indicators of eye health or disease. By utilizing data collected from bedside imaging, the research aims to enhance diagnostic methods and improve care for infants with ROP.

Who could benefit from this research

Good fit: Ideal candidates for this research include premature infants who have been evaluated for ROP and healthy term infants used as a comparison group.

Not a fit: Patients who are older than 21 years or those who do not have a history of ROP or were not part of the original studies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic techniques and treatment strategies for infants at risk of vision impairment due to ROP.

How similar studies have performed: Previous studies using OCT imaging in similar populations have shown promising results, indicating that this approach could yield valuable insights.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.