Analyzing proteins in individual cells to understand diseases better
Official title: Advanced Single-Cell Protein Analysis with Multiplex in Situ Tagging Array Technology
Funded at State University New York Stony Brook · NIH-11017811 · Data updated 2026-11-12
This study is testing a new technology that helps scientists look closely at proteins in individual cells, which could lead to better ways to diagnose and treat diseases, ultimately benefiting patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project start | February 1, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $354,551 |
| NIH project number | 5R35GM151972-02 |
| Project ID | NIH-11017811 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with conditions that involve significant cellular changes, such as cancer or autoimmune diseases.
✕Less likely to help
Patients with stable, non-progressive conditions that do not involve cellular dysfunction may not benefit from this research.
What this research studies
This research focuses on developing a new technology called multiplex in situ tagging array technology to analyze proteins at the single-cell level. By using this innovative approach, researchers aim to detect and quantify a wide range of proteins within individual cells, which is crucial for understanding cellular functions and disease mechanisms. The technology can also identify surface proteins on smaller pathogens, potentially aiding in disease prognosis and treatment. Patients may benefit from insights gained through this research, which could lead to improved diagnostic and therapeutic strategies.
Why it matters
Potential benefit: If successful, this research could lead to more accurate disease diagnosis and personalized treatment options for patients.
How similar studies have gone: Previous research has shown promise in single-cell analysis techniques, but this specific multiplex approach is relatively novel and untested.
Where this research is happening
-
State University New York Stony Brook
Stony Brook, United States Active
Researchers
- Principal investigator: Wang, Jun — State University New York Stony Brook
- Study coordinator: Wang, Jun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.