Analyzing proteins in individual cancer cells to improve treatment
Official title: In-depth and label-free proteome profiling of hundreds of single cells per day
Funded at Brigham Young University · NIH-10908311 · Data updated 2026-11-12
This study is looking at the different types of cells in cancer tissues by examining proteins one cell at a time, which could help doctors create better treatments that are specially designed for each person's cancer.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham Young University NIH-funded |
| Lab location | 1 site (Provo, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $181,717 |
| NIH project number | 5R21CA272326-03 |
| Project ID | NIH-10908311 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with various types of cancer who are seeking innovative treatment options.
✕Less likely to help
Patients with non-cancerous conditions or those not currently undergoing cancer treatment may not benefit from this research.
What this research studies
This research focuses on understanding the diverse types of cells present in cancer tissues by analyzing proteins at the single-cell level. By using advanced mass spectrometry techniques, the study aims to quantify protein expression in a large number of cancer cells, which can provide insights that traditional bulk studies cannot. This approach will help identify different cell populations and their functions, potentially leading to better diagnostics and more effective cancer treatments. Patients may benefit from improved therapeutic strategies tailored to the specific characteristics of their cancer.
Why it matters
Potential benefit: If successful, this research could lead to more precise cancer treatments based on the unique protein profiles of individual tumors.
How similar studies have gone: Other research has shown promising results using similar mass spectrometry techniques for single-cell analysis, indicating a strong potential for success in this area.
Where this research is happening
-
Brigham Young University
Provo, United States Active
Researchers
- Principal investigator: Kelly, Ryan T — Brigham Young University
- Study coordinator: Kelly, Ryan T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.