Analyzing newborn blood samples to find markers for SIDS risk

Dried blood spot proteomics analysis of newborn screening cards to identify prognostic markers of SIDS risk

NIH-funded research Boston Children's Hospital · NIH-10734386

This study is looking at tiny clues in dried blood samples from newborns to see if they can help us understand the risk of Sudden Infant Death Syndrome (SIDS), with the hope that finding these clues early on could lead to ways to keep babies safer.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionBoston Children's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10734386 on NIH RePORTER

What this research studies

This research investigates the potential biological markers in dried blood samples from newborns that could indicate a risk for Sudden Infant Death Syndrome (SIDS). By examining blood samples from infants who later died of SIDS and comparing them to those who died from known causes, the study aims to identify abnormalities that may be present at birth. The goal is to uncover whether these markers can help predict SIDS risk early in life, allowing for possible interventions. The research utilizes advanced proteomics techniques to analyze the proteins present in these blood samples.

Who could benefit from this research

Good fit: Ideal candidates for this research are newborns, particularly those who may be at higher risk for SIDS due to family history or other factors.

Not a fit: Patients who are older infants or children who have already surpassed the critical risk period for SIDS may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the identification of early warning signs for SIDS, potentially saving lives through timely interventions.

How similar studies have performed: While research into SIDS has been ongoing, this specific approach using dried blood spots for early risk identification is relatively novel and has not been extensively tested.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.