Analyzing MRI to predict aggressive prostate cancer in African American men
Official title: Racially-associated MRI analysis and modeling for predicting aggressive prostate cancer
Funded at University of California Los Angeles · NIH-11065578 · Data updated 2026-11-12
This study is looking to make it easier to spot aggressive prostate cancer in African American men by using advanced MRI techniques that take into account specific traits related to race, helping doctors get better and more accurate results.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 15, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $82,119 |
| NIH project number | 3R01CA272702-02S1 |
| Project ID | NIH-11065578 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are African American men who are at risk for or have been diagnosed with prostate cancer.
✕Less likely to help
Patients who are not African American or those without prostate cancer may not benefit from this research.
What this research studies
This research focuses on improving the detection of aggressive prostate cancer in African American men by utilizing advanced MRI techniques. It aims to enhance the current imaging interpretation system, known as PI-RADS, by incorporating racially associated characteristics that affect MRI results. The study will analyze differences in tumor detection rates between African American and Caucasian men, particularly in the transition zone of the prostate. By developing a portable perfusion phantom to standardize measurements, the research seeks to improve the accuracy and reliability of MRI assessments across different medical facilities.
Why it matters
Potential benefit: If successful, this research could lead to more accurate prostate cancer diagnoses for African American men, potentially improving treatment outcomes.
How similar studies have gone: Previous research has indicated that incorporating racial factors into medical imaging can improve diagnostic accuracy, suggesting a promising avenue for this approach.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Sung, Kyung Hyun — University of California Los Angeles
- Study coordinator: Sung, Kyung Hyun
Related research
Other NIH-funded projects on the same topics.
-
Cardiovascular risk planning and reduction for men with prostate cancer
A program to better predict and reduce heart disease risk in men treated for prostate cancer, especially older patients.
-
Effects of ADT on motivation and emotion in prostate cancer patients
This project looks at how androgen deprivation therapy may affect motivation and mood over time in men with prostate cancer.
-
Causal Protein Markers to Understand and Predict Prostate Cancer Risk in Africans and Europeans
A cancer research project looking at proteins linked to prostate cancer to better understand why it happens and how risk differs between African and European populations.
-
Ethical multimodal AI platform to improve prostate cancer detection with ultrasound
A patient-friendly AI system uses ultrasound and MRI information to help doctors better find prostate cancer, aiming to improve accuracy and access.
-
Characterizing epigenetic targets in prostate cancer to help AR-driven cancer
A research project at MD Anderson aims to understand how epigenetic factors shape androgen receptor signaling in prostate cancer to find new ways to treat resistant forms of the disease.
-
AR and RNA-binding in prostate cancer resistance
A cancer research grant exploring how the androgen receptor’s interaction with RNA may drive treatment resistance in prostate cancer, with potential to guide new therapies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.