Analyzing lung tissue images to understand fibrosis and cell aging
Official title: Imaging and Image Analysis Core
Funded at University of Colorado Denver · NIH-10815865 · Data updated 2026-11-12
This study is looking at lung tissue samples from people with idiopathic pulmonary fibrosis (IPF) to better understand how certain proteins and messages in our cells behave, using special imaging techniques to help improve research on lung health.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $205,392 |
| NIH project number | 5P01HL162607-02 |
| Project ID | NIH-10815865 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with idiopathic pulmonary fibrosis or related lung conditions.
✕Less likely to help
Patients with lung diseases not related to fibrosis or those without a diagnosis of idiopathic pulmonary fibrosis may not benefit from this research.
What this research studies
This research focuses on analyzing human lung tissues to investigate the spatial and cellular localization of mRNAs and protein expression levels. It employs advanced imaging techniques, including immunofluorescence and label-free imaging, to study conditions like fibrosis and cell senescence in idiopathic pulmonary fibrosis (IPF) lungs. By centralizing these imaging efforts, the project aims to provide high-quality data that can enhance collaboration across various research projects. Patients' lung samples will be carefully stained and imaged to assess critical biological processes affecting lung health.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with lung diseases, particularly those suffering from fibrosis.
How similar studies have gone: Previous research utilizing advanced imaging techniques in lung tissue analysis has shown promising results, indicating that this approach is both relevant and potentially impactful.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Dobrinskikh, Evgenia — University of Colorado Denver
- Study coordinator: Dobrinskikh, Evgenia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.