Analyzing individual exosomes to discover biomarkers and understand their functions
Multi-omics profiling of individual exosomes for origin-tracing, biomarker discovery, and biological function characterization
This study is exploring a new way to look at tiny particles released by cells, called extracellular vesicles, to find important information that could help improve tests and treatments for different diseases.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wellsim Biomedical Technologies, INC. NIH-funded |
| Lab location | 1 site (San Jose, UNITED STATES) |
| Project ID | NIH-10919626 on NIH RePORTER |
What this research studies
This research focuses on the detailed analysis of extracellular vesicles (EVs), which are tiny particles released by cells that carry important biological information. By developing a new technology that allows for the profiling of individual EVs, the research aims to uncover variations in gene expression and surface proteins that traditional methods overlook. This approach utilizes advanced sequencing techniques to provide a comprehensive view of EVs, potentially leading to improved diagnostics and targeted therapies for various diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions that involve extracellular vesicle changes, such as certain cancers or metabolic disorders.
Not a fit: Patients with conditions unrelated to extracellular vesicle biology may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more accurate diagnostic tools and personalized treatment options for patients.
How similar studies have performed: Previous research has shown promise in using single-EV analysis for biomarker discovery, indicating that this approach could yield significant advancements.
Where this research is happening
San Jose, UNITED STATES
- Wellsim Biomedical Technologies, INC. — San Jose, United States (Active)
Researchers
- Principal investigator: Chen, Yuchao — Wellsim Biomedical Technologies, INC.
- Study coordinator: Chen, Yuchao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.