Analyzing individual cells to improve diagnostics and treatments
Official title: Mass Spectrometry-Based Biochemical Analysis of Single Cells Beyond the Global Proteome
Funded at Brigham Young University · NIH-10836936 · Data updated 2026-11-12
This study is looking at how individual cells in our bodies behave by using special techniques to analyze their proteins and other important molecules, which could help us find better ways to diagnose and treat different health conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham Young University NIH-funded |
| Lab location | 1 site (Provo, United States) |
| Project start | September 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $469,543 |
| NIH project number | 1R35GM153179-01 |
| Project ID | NIH-10836936 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that exhibit cellular heterogeneity, such as cancer or autoimmune diseases.
✕Less likely to help
Patients with conditions that do not involve significant cellular diversity or those who are not undergoing treatment may not benefit from this research.
What this research studies
This research focuses on understanding the complex behaviors of individual cells within biological tissues by using advanced mass spectrometry techniques. By examining the proteins, lipids, and metabolites at the single-cell level, the study aims to uncover the unique characteristics and functions of different cell populations. This approach allows for a more detailed analysis than traditional bulk methods, potentially leading to better diagnostic tools and more effective treatments for various conditions. The research will develop new technologies to enhance the profiling of biomolecules, providing insights into cellular functions and disease mechanisms.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnostics and personalized treatments for patients based on their unique cellular profiles.
How similar studies have gone: Previous research using mass spectrometry for single-cell analysis has shown promising results, indicating that this approach has the potential for significant advancements in biomedical research.
Where this research is happening
-
Brigham Young University
Provo, United States Active
Researchers
- Principal investigator: Kelly, Ryan T — Brigham Young University
- Study coordinator: Kelly, Ryan T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.