Analyzing individual cells in brain tumors using advanced sequencing techniques
Core 1: Tumor Processing and Single Cell RNA sequencing Core
This study is looking at the different types of cells in brain tumors, especially glioblastoma, to help us understand how these tumors grow and how our immune system responds, which could lead to new treatments for patients like you.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10876417 on NIH RePORTER |
What this research studies
This research focuses on using single cell RNA sequencing to explore the cellular makeup of brain tumors, particularly glioblastoma. By examining individual cells, researchers aim to understand the different states of immune and malignant cells within the tumor environment. The project involves both patient samples and animal models, utilizing advanced technologies and expert personnel to ensure high-quality data generation. This approach could lead to better insights into tumor biology and potential therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with glioblastoma or other brain tumors who are undergoing treatment.
Not a fit: Patients with non-cancerous conditions or those not diagnosed with brain tumors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for patients with brain tumors.
How similar studies have performed: Previous studies using single cell RNA sequencing have shown promising results in understanding tumor biology and improving treatment strategies.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Wucherpfennig, Kai W — Brigham and Women's Hospital
- Study coordinator: Wucherpfennig, Kai W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.