Analyzing individual bacterial cells to understand antibiotic resistance
Single Cell Analysis Core (Core C)
This study is looking at how different bacteria react to antibiotics by checking their genes and how they use energy, so we can better understand why some bacteria are tougher to treat, and it’s designed to help researchers who are working on antibiotic resistance.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11037947 on NIH RePORTER |
What this research studies
This research focuses on examining how individual bacterial cells respond to antibiotics by analyzing their gene expression and metabolic processes. Using advanced techniques, the project aims to create a controlled environment where bacterial cells can be cultured and studied at a single-cell level. The research will involve measuring how these cells vary in their resistance to antibiotics and understanding the underlying mechanisms of this variation. By providing a centralized platform for these analyses, the project seeks to support multiple related studies in the field of antibiotic resistance.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with bacterial infections that are resistant to standard antibiotic treatments.
Not a fit: Patients with non-bacterial infections or those who do not have antibiotic-resistant infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for combating antibiotic resistance in bacterial infections.
How similar studies have performed: Previous research has shown success in using single-cell analysis to study antibiotic resistance, indicating that this approach is both promising and validated.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Kim, Minsu — Emory University
- Study coordinator: Kim, Minsu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.