Analyzing immune responses to HIV vaccine candidates
Official title: Project 2: Immune Response Analysis
Funded at Scripps Research Institute, the · NIH-11076804 · Data updated 2026-11-12
This study is looking at how well new HIV vaccines can get your immune system to fight the virus, so we can make better vaccines in the future to help protect you and others.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Scripps Research Institute, the NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | June 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $544,881 |
| NIH project number | 5P01AI177683-03 |
| Project ID | NIH-11076804 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include healthy adults aged 21 and older who are HIV-naive and willing to participate in vaccine trials.
✕Less likely to help
Patients who are already HIV-positive or have a history of severe allergic reactions to vaccine components may not benefit from this research.
What this research studies
This research focuses on understanding how the immune system responds to potential HIV vaccines by using advanced techniques to analyze immune responses. The team will conduct trials to evaluate how well these vaccines activate specific immune cells and antibodies in the body. By gathering detailed information from these trials, the researchers aim to improve the design and effectiveness of future HIV vaccines, ultimately leading to better protection against the virus.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective HIV vaccines, providing better protection for individuals at risk of HIV infection.
How similar studies have gone: Previous research has shown promise in using multi-omics approaches to enhance vaccine development, indicating that this methodology could yield significant insights.
Where this research is happening
-
Scripps Research Institute, the
La Jolla, United States Active
Researchers
- Principal investigator: Briney, Bryan — Scripps Research Institute, the
- Study coordinator: Briney, Bryan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.