Analyzing genetic mutations in cancer to improve treatment
Official title: GDANII_DLBCL cohort analysis and cloud costs
Funded at Broad Institute, INC. · NIH-11191176 · Data updated 2026-11-12
This study is looking at the genetic changes that cause cancer to help doctors find better, personalized treatments for cancer patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Broad Institute, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | December 1, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $10,175 |
| NIH project number | 3U24CA264024-04S1 |
| Project ID | NIH-11191176 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are cancer patients who have undergone genetic testing or have specific mutations identified in their tumors.
✕Less likely to help
Patients with non-cancerous conditions or those whose tumors do not have identifiable genetic mutations may not benefit from this research.
What this research studies
This research focuses on understanding the genetic mutations that lead to cancer by analyzing the cancer genome. The team at the Broad Institute will create a Genome Data Analysis Center to characterize point mutations and other genetic changes in cancer patients. They will use advanced tools to study both coding and non-coding regions of the genome, including DNA methylation and epigenomic data, to uncover the biological mechanisms driving cancer. This comprehensive approach aims to provide insights that can inform personalized treatment strategies for cancer patients.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized cancer treatments based on individual genetic profiles.
How similar studies have gone: Previous research has shown success in using genomic analysis to inform cancer treatment, indicating that this approach is promising and builds on established methodologies.
Where this research is happening
-
Broad Institute, INC.
Cambridge, United States Active
Researchers
- Principal investigator: Getz, Gad a — Broad Institute, INC.
- Study coordinator: Getz, Gad a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.