Analyzing genetic mutations in cancer to improve treatment
GDANII_DLBCL cohort analysis and cloud costs
['FUNDING_OTHER'] · BROAD INSTITUTE, INC. · NIH-11191176
This study is looking at the genetic changes that cause cancer to help doctors find better, personalized treatments for cancer patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BROAD INSTITUTE, INC. (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-11191176 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the genetic mutations that lead to cancer by analyzing the cancer genome. The team at the Broad Institute will create a Genome Data Analysis Center to characterize point mutations and other genetic changes in cancer patients. They will use advanced tools to study both coding and non-coding regions of the genome, including DNA methylation and epigenomic data, to uncover the biological mechanisms driving cancer. This comprehensive approach aims to provide insights that can inform personalized treatment strategies for cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients who have undergone genetic testing or have specific mutations identified in their tumors.
Not a fit: Patients with non-cancerous conditions or those whose tumors do not have identifiable genetic mutations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized cancer treatments based on individual genetic profiles.
How similar studies have performed: Previous research has shown success in using genomic analysis to inform cancer treatment, indicating that this approach is promising and builds on established methodologies.
Where this research is happening
CAMBRIDGE, UNITED STATES
- BROAD INSTITUTE, INC. — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GETZ, GAD A — BROAD INSTITUTE, INC.
- Study coordinator: GETZ, GAD A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: cancer cell genome, cancer genome, Cancer Patient, cancer sub-types, cancer subtypes