Analyzing genetic factors in prostate cancer treatment and outcomes
Genomics Core
This study is looking at the genes in prostate tumors and blood samples to find out how they affect treatment success and long-term health for men with prostate cancer, so we can better understand the disease and improve care for patients like you.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10922784 on NIH RePORTER |
What this research studies
This research focuses on the molecular analysis of prostate tumors and DNA from blood samples to understand genetic factors that influence treatment responses and long-term outcomes in prostate cancer patients. The Genomics Core will conduct detailed sequencing of specific genes related to DNA damage repair and integrate this data with existing genomic information to identify mutations that may increase cancer risk or affect treatment efficacy. By sharing this genomic data with the broader scientific community, the research aims to enhance understanding of prostate cancer genetics and improve patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research are men diagnosed with prostate cancer who are undergoing treatment and have available tumor and blood samples.
Not a fit: Patients with non-prostate cancers or those who do not have available biological samples for analysis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized treatment strategies for prostate cancer patients based on their genetic profiles.
How similar studies have performed: Previous research has shown success in using genomic analysis to identify mutations in cancer patients, indicating that this approach is promising and has been validated in similar contexts.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Solit, David B. — Sloan-Kettering Inst Can Research
- Study coordinator: Solit, David B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.