Analyzing genetic changes in human tissues over time
Computational genomic analysis of genomic variations in human tissues
This study is looking at how our genes change over time in different parts of our bodies because of aging and things around us, and it aims to help people understand how these changes might affect their health, especially for conditions like cancer and autoimmune diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project ID | NIH-10933392 on NIH RePORTER |
What this research studies
This research investigates how genetic variations accumulate in human tissues due to factors like aging and environmental exposures. By utilizing advanced genomic technologies, the study aims to understand the patterns of somatic mutations that occur in both healthy and diseased tissues. The approach involves detailed computational analysis to characterize these mutations and their potential implications for various health conditions, including cancer and autoimmune diseases. Patients may benefit from insights into how these genetic changes affect their health and disease progression.
Who could benefit from this research
Good fit: Ideal candidates include individuals with a history of genetic disorders, autoimmune diseases, or those at risk for cancers.
Not a fit: Patients with stable, non-genetic conditions or those not affected by the diseases being studied may not receive direct benefits.
Why it matters
Potential benefit: If successful, this research could lead to improved early diagnosis and personalized treatment strategies for various diseases.
How similar studies have performed: Other research has shown success in understanding genetic variations in tissues, suggesting that this approach could yield valuable insights.
Where this research is happening
Newark, UNITED STATES
- Rutgers Biomedical and Health Sciences — Newark, United States (Active)
Researchers
- Principal investigator: De, Subhajyoti — Rutgers Biomedical and Health Sciences
- Study coordinator: De, Subhajyoti
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.