Analyzing genetic changes in diverse tumors to improve cancer treatment
Statistical methods for genomic analysis of heterogeneous tumors
This study is looking at the different genetic changes in tumors to see how they grow and respond to treatments, with the goal of helping doctors provide better care for cancer patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10892163 on NIH RePORTER |
What this research studies
This research investigates the complex genetic and molecular variations found in tumors, which can affect how they evolve and respond to treatment. By using advanced statistical methods, the study aims to analyze both genomic and transcriptomic data from cancer cells to better understand their evolutionary dynamics. This approach will help identify how these variations relate to cancer prognosis and treatment responses, ultimately aiming to enhance clinical management for cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients with heterogeneous tumors who are undergoing treatment or have recently completed treatment.
Not a fit: Patients with non-cancerous conditions or those whose tumors do not exhibit significant genetic diversity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for cancer patients based on their unique tumor characteristics.
How similar studies have performed: Previous studies using similar integrative approaches have shown promise in enhancing our understanding of cancer evolution and treatment responses.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Wang, Wenyi — University of Tx Md Anderson Can Ctr
- Study coordinator: Wang, Wenyi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.