Analyzing gene expression in individual cells to understand cancer better
Core B: Bioinformatics & Biostatistics Core
['FUNDING_P01'] · UNIVERSITY OF TX MD ANDERSON CAN CTR · NIH-10907494
This study is looking at how individual cells in cancer behave and communicate, using a special technology to find rare cell types that could help us understand the disease better, with the hope of creating more personalized treatments for patients like you.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TX MD ANDERSON CAN CTR (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10907494 on ClinicalTrials.gov |
What this research studies
This research focuses on using advanced single cell RNA sequencing (scRNA-seq) technology to analyze the gene expression of individual cells. By identifying distinct cellular subsets and modeling developmental lineage hierarchies, the research aims to uncover rare cell types that are often hidden in traditional bulk RNA sequencing data. The Bioinformatics and Biostatistics Core will provide essential data analysis and biostatistical support to enhance the understanding of cancer biology and improve treatment strategies. Patients may benefit from insights gained through this research that could lead to more personalized therapies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals diagnosed with various types of cancer, particularly those who are 21 years or older.
Not a fit: Patients with non-cancerous conditions or those under 21 years of age may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments by revealing critical insights into cellular behavior and diversity.
How similar studies have performed: Previous research utilizing single cell RNA sequencing has shown promising results in understanding cancer heterogeneity and has led to significant advancements in the field.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TX MD ANDERSON CAN CTR — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YI, S. STEPHEN — UNIVERSITY OF TX MD ANDERSON CAN CTR
- Study coordinator: YI, S. STEPHEN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.