Analyzing facial expressions in early psychosis

Computational phenotyping of face expression in early psychosis

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-11009577

This study is looking at how certain facial expressions, like flat or less expressive faces, might be linked to early signs of schizophrenia, and it uses special technology to measure these expressions during interviews to help better understand and support people who may be at risk for psychosis.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11009577 on NIH RePORTER

What this research studies

This research investigates how facial expressions, particularly blunted or flat expressions, are associated with schizophrenia and its early warning signs. By using advanced computational methods, the study aims to objectively measure facial muscle movements during interviews and viewing tasks. This approach will help create a standardized way to assess facial expressions, which could improve understanding and treatment of individuals at risk for psychosis.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with schizophrenia spectrum disorders or those identified as clinically high risk for psychosis.

Not a fit: Patients with no history of psychosis or related disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for individuals with schizophrenia and those at high risk.

How similar studies have performed: Other research has shown promise in using computational methods to analyze facial expressions, suggesting this approach could yield valuable insights.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.