Analyzing dried blood samples to understand sepsis better
Multiomic, mass spectrometry-based analysis of dried blood for deep phenotyping of sepsis
This study is looking at how sepsis affects people, especially those recovering from severe COVID-19, by analyzing dried blood samples to find important proteins and substances that can help us understand the disease better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11051199 on NIH RePORTER |
What this research studies
This research focuses on sepsis, a severe condition caused by infections that can lead to organ failure and death. It aims to analyze dried blood samples using advanced mass spectrometry techniques to identify proteins and metabolites that can provide insights into the disease's progression and long-term effects. By utilizing innovative sampling methods, the study seeks to improve the understanding of sepsis and its impact on patients, particularly those recovering from severe COVID-19. The research involves collecting blood samples from patients in intensive care and outpatient settings to create a comprehensive profile of sepsis.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients who have experienced sepsis, particularly those recovering from severe COVID-19.
Not a fit: Patients who have not had sepsis or are not recovering from severe infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for sepsis, ultimately improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using similar multiomic approaches to understand complex diseases, indicating potential for success in this area.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Foster, Matthew Wolf — Duke University
- Study coordinator: Foster, Matthew Wolf
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.