Analyzing cognitive health and decline in diverse populations
DISCOVERY - Statistics and Analysis Core
['FUNDING_OTHER'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10929419
This study is looking to track and understand changes in thinking and memory over two years for people at risk of cognitive decline, using advanced tools to help identify what affects these changes, so we can better support those who may face challenges like dementia.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10929419 on ClinicalTrials.gov |
What this research studies
This research focuses on developing and implementing a comprehensive neurocognitive assessment to evaluate cognitive health over time, particularly in populations at risk for cognitive decline. The study will utilize advanced statistical methods, including machine learning, to analyze cognitive outcomes and identify factors influencing cognitive trajectories. Patients will undergo repeated cognitive evaluations over a two-year period, allowing for detailed tracking of changes in cognitive function. The research aims to improve understanding of cognitive impairment and dementia, especially in disparity populations.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for cognitive decline, particularly those from diverse and disparity populations.
Not a fit: Patients with stable cognitive function and no risk factors for cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better identification and management of cognitive decline, ultimately improving patient outcomes and care strategies.
How similar studies have performed: Previous studies, such as the Atherosclerosis Risk in Communities (ARIC) study, have successfully utilized similar cognitive assessment methods, indicating potential for success in this research.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOTTESMAN, REBECCA F — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: GOTTESMAN, REBECCA F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.