Analyzing chemicals in maternal and cord blood samples to improve detection methods
Non-target analysis of maternal and cord blood samples: Advancing computational tools and discovering novel chemicals
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11065494
This study is looking at blood samples from pregnant women to find out how different chemicals might affect pregnancy and baby health, with the goal of helping to understand risks like preterm birth.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-11065494 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the analysis of maternal and cord blood samples to identify a wide range of chemicals that may affect pregnancy outcomes. By developing advanced computational tools, the project aims to improve the detection of both industrial chemicals and naturally occurring metabolites in these samples. The study will utilize high-resolution mass spectrometry to analyze blood samples from pregnant women in Northern California, aiming to uncover potential links between chemical exposure and health outcomes such as preterm birth. This innovative approach seeks to provide a more comprehensive understanding of the human exposome during critical developmental periods.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women from Northern California who are willing to provide blood samples for analysis.
Not a fit: Patients who are not pregnant or those who do not reside in Northern California may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of chemical exposures during pregnancy, potentially improving maternal and fetal health outcomes.
How similar studies have performed: Previous research has shown promise in using non-targeted analysis to identify environmental chemicals, indicating that this approach could yield significant insights.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ABRAHAMSSON, DIMITRI — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: ABRAHAMSSON, DIMITRI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.