Analyzing cellular and molecular characteristics of gastric conditions
Official title: Core B: Translational, Cellular and Molecular Analysis
Funded at Stanford University · NIH-10932186 · Data updated 2026-11-12
This study is looking at tissue samples from people with stomach issues to learn more about early signs of cancer, using advanced technology to help find better ways to detect and treat these conditions.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | September 20, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $429,963 |
| NIH project number | 5P01CA265772-02 |
| Project ID | NIH-10932186 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are individuals with precancerous gastric conditions or those undergoing gastric biopsies.
✕Less likely to help
Patients with non-gastric conditions or those not undergoing any tissue sampling may not benefit from this research.
What this research studies
This research focuses on the analysis of human tissue samples to understand the cellular and molecular characteristics of gastric conditions, particularly precancerous states. It employs advanced techniques such as RNA sequencing, single-cell genomics, and spatial transcriptomics to gather detailed information about the gastric microenvironment. By utilizing a centralized core facility, the project aims to streamline data production and ensure consistency in sample processing. Patients' biopsies and organoid samples will be analyzed to provide insights that could lead to improved detection and treatment strategies for gastric diseases.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment options for patients with gastric conditions.
How similar studies have gone: Previous research utilizing similar genomic and imaging techniques has shown promise in enhancing our understanding of cancer biology and improving patient outcomes.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Amieva, Manuel R — Stanford University
- Study coordinator: Amieva, Manuel R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.