Analyzing cancer data using advanced bioinformatics techniques
Official title: Comprehensive Analysis and Multi-Omics Data Integration for Cancer-Related Studies
Funded at Johns Hopkins University · NIH-10978439 · Data updated 2026-11-12
This study is looking at different biological information about cancer, like how genes are changed and how the immune system reacts, to help us understand how tumors respond to treatments like immunotherapy, with the hope of finding better, more personalized options for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 18, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $156,704 |
| NIH project number | 2R50CA243627-06 |
| Project ID | NIH-10978439 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with various types of cancer who are undergoing or considering immunotherapy.
✕Less likely to help
Patients with non-cancerous conditions or those not receiving any form of cancer treatment may not benefit from this research.
What this research studies
This research focuses on integrating and analyzing various types of biological data related to cancer, including DNA methylation and immune responses. By utilizing advanced bioinformatics tools and multi-omics approaches, the project aims to uncover insights into how tumors respond to treatments like immunotherapy. Patients may benefit from improved understanding of their cancer's biology, which could lead to more personalized treatment options. The research involves collaboration with multiple cancer investigators to enhance data analysis and interpretation.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments based on a deeper understanding of tumor biology.
How similar studies have gone: Previous research has shown success in using multi-omics approaches to improve cancer treatment outcomes, indicating that this methodology is promising.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Danilova, Ludmila — Johns Hopkins University
- Study coordinator: Danilova, Ludmila
Related research
Other NIH-funded projects on the same topics.
-
Targeting hidden brain injuries in iTTP to improve long-term brain health
A researcher aims to find out how silent brain injuries in people with immune thrombotic thrombocytopenic purpura (iTTP) happen, how they affect thinking and stroke risk, and how to prevent them.
-
Accelerated flap coverage for severe leg injuries: earlier reconstruction vs standard timing
This study tests whether doing early flap coverage after a severe leg injury lowers infection risk and improves healing for patients with open wounds and bone injury.
-
Placebo-controlled shunting for iNPH: does the surgery help with walking and balance?
A doctor-led trial at Johns Hopkins will test whether a shunt surgery improves walking and balance in older adults with idiopathic normal pressure hydrocephalus.
-
Omalizumab for COPD patients with allergen sensitization and exposure
A multicenter trial will test whether adding omalizumab helps people with COPD who are allergic to common indoor allergens and are exposed to them.
-
Johns Hopkins Total Worker Health Center focusing on mental health
A nationwide center at Johns Hopkins is working to improve mental health and well-being among workers by studying workplace health strategies and translating findings into practical tools.
-
Role of fat droplets in liver fat and inflammatory signals in NAFLD
A study at Johns Hopkins will explore how fat droplets in the liver influence molecules that drive inflammation and progression of non-alcoholic fatty liver disease (NAFLD) in adults.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.