Analyzing breast tissue composition to improve cancer diagnosis

Lesion Composition and Quantitative Imaging Analysis on Breast Cancer Diagnosis

NIH-funded research University of Hawaii at Manoa · NIH-10894931

This study is looking at new imaging methods to help doctors better tell the difference between cancerous and non-cancerous breast lumps, which could lead to fewer unnecessary biopsies and more accurate breast cancer screenings for patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Hawaii at Manoa NIH-funded
Lab location1 site (Honolulu, United States)
Project IDNIH-10894931 on NIH RePORTER

What this research studies

This research investigates how the composition of breast lesions can be analyzed using advanced imaging techniques to improve the accuracy of breast cancer diagnoses. By utilizing multispectral imaging to measure the lipid, water, and protein content of suspicious lesions, the study aims to differentiate between malignant and benign tissues more effectively. The goal is to reduce unnecessary biopsies and enhance the diagnostic yield of breast cancer screenings. Patients will be evaluated using a combination of biological markers and quantitative imaging analysis to determine the best approach for diagnosis.

Who could benefit from this research

Good fit: Ideal candidates for this research are women aged 40-79 with dense breast tissue who are undergoing routine breast cancer screening.

Not a fit: Patients with non-dense breast tissue or those who are not undergoing breast cancer screening may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate breast cancer diagnoses and fewer unnecessary biopsies for patients.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for cancer detection, suggesting that this approach may yield beneficial results.

Where this research is happening

Honolulu, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast CancerBreast Cancer DetectionBreast Cancer Early DetectionBreast Cancer Early ScreeningBreast cancer screening
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.